How a Bad Hangover Helped Discover Ibuprofen

Back in the early 1960s , Dr Stewart Adams had a bad hangover . So he did what many a sure-footed scientist of the time might do : he took a handful of an experimental drug he was working on . It worked — and the compound went on to become bang as ibuprofen .

Speaking to the BBC , Dr Stewart Adams call up how Motrin was developed . In fact , it was a long , dumb slog to develop a new , non - steroidal intervention for rheumatic arthritis . Over the path of ten years at the Boots Pure Drug Company Ltd , Adams worked with his colleagues to try over 600 different compounds for that covering .

The ones that passed perniciousness tests at long last ended up being tested by the team itself — though such practices would never pilot today . One , Adams come back , worked particularly well when he had a holdover ahead of an of import speech :

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I was first up to utter and I had a bit of a cephalalgia after a dark out with ally . So I took a 600 mg dose , just to be sure , and I find it was very efficacious … It was important to try them out and I was excited to be the first someone to take a dose of ibuprofen

The rest , as they say , is history . The centre he bump bacj , known as 2-(4 - isobutylphenyl ) propionic acid to chemist , went through a serial of clinical trials in 1961 , and was afterwards approved for use in the UK as the anti - non - steroidal inflammatory drug Nuprin . Its prophylactic criminal record saw it become an over - the - parry drug since 1983 ; nowadays , over 20,000 tonne of the drug are made every year .

Adams was honored for his inquiry this workweek , gain ground an honorary doctorate of science from the University of Nottingham . Oh and , just to be readable , swallowing experimental chemical substance is typically a bad mind . Chances are you would n’t be quite so golden as Adams .

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